Von Willebrand Disease (VWD) and Heavy Menstrual Bleeding

Five Liters, a pioneer in wearable neurostimulation for
bleeding disorders, invites you to participate in an
extraordinary clinical trial focusing on the impacts of
wearable neurostimulation on heavy menstrual bleeding and
We need forward-thinking women diagnosed with Type 1
VWD who also experience heavy menstrual bleeding to help
us validate this novel treatment option from the comfort of
Eligible participants who complete the study will be
compensated a total $200 for their time.

Click here to take part
Haga clic aquí para participar
Klik hier om deel te nemen

Study for

Estudio dirigido a

Zielgrupper der Studie

Onderzoek voor:

Women aged 18-45 with VWD & Heavy Menstrual Bleeding

Sponsored by

Patrocinado por

Gesponsert von


Five Liters








Participate by

Participar mediante


Duur van onderzoek:

What is expected of me? 

¿Qué se espera de mí?

Was wird von mir erwartet?

Wat wordt van mij verwacht?

Participants must be available during two consecutive menstrual cycles and be willing to:

  • Estimate blood loss daily during menstruation
  • Measure menstruation duration
  • Assess quality of life 
  • Use a non-invasive neurostimulation device from the comfort of their home during menstruation

Participate from the comfort of your home.

Five Liters will ship the Volta wearable neurostimulation device and instructions for use directly to qualified participants. Data will be self-reported and aggregated into the overall clinical trial results. The first set of measures will be taken during the first cycle under normal conditions, and the second set of measures will be taken during the second cycle with added daily neurostimulation.

Contact our study team

What is the benefit for me?

¿En qué me beneficia?

Welchen Nutzen habe ich davon?

Wat is het voordeel voor mij?

● You will be compensated for your time.

● Our Ultimate Goal: To offer the 3 million individuals in
the U.S. affected by VWD and heavy menstrual
bleeding a safer, non-pharmaceutical, and non-
invasive solution for an improved quality of life.
● Help Support a Brighter Future for Women With von
Willebrand Disease.

Who is the study for? 

¿A quién va dirigido el estudio?

Für wen ist die Studie geeignet?

Voor wie is het onderzoek bedoeld?

You may be eligible to support this pioneering clinical trial if you:

  • Are diagnosed with von Willebrand Disease Type 1 
  • Have a history of heavy menstrual bleeding
  • Are Between the ages of 18-45
  • Have not been pregnant at any point in the past 3 months
  • Are not currently lactating
  • Do not have a history of tobacco use, ingested nicotine via smoking, vaping, smokeless tobacco, or nicotine patches in the past 3 months
  • Do not have a pacemaker, cochlear implant, or implanted neurostimulation system
  • Have reliable access to an internet enabled device

Complete this questionnaire to take part.

Fülle diesen Fragebogen aus, um herauszufinden, ob Du berechtigt bist