PROGRESS: A study for people who have recovered from depression

The University of Oxford is looking for healthy volunteers aged 18-55 years, who have recovered from two or more episodes of depression, for a study investigating how a licensed drug (prucalopride) affects thinking and emotion.

The study involves 2 study visits over a period of 1-2 weeks at the Warneford Hospital Site, Oxford.

You will be reimbursed £125 for your time and inconvenience. Reasonable travel expenses will be reimbursed.

Click here to take part

Study For

Zielgruppe der Studie

Adults who have recovered from depression

Sponsored By

Gesponsert von

The University of Oxford






Participate by


December 31, 2023


What is expected of me? 

Was wird von mir erwartet?

If you are happy to take part in the research the screening process has two parts:

> Part 1 is when your suitability for the study is checked and you have the opportunity to ask questions. This can be conducted remotely via a Microsoft team meeting.

> Part 2: Will be held at the Department of Psychiatry in the Warneford Hospital, Oxford. If you are eligible for the study, you will then complete some baseline questionnaires and computer tasks. You will then receive 7 days of medication to take home with you - either prucalopride (a licenced drug) or placebo


During the study at home:

> You will receive text reminders to help you remember to take the medication at roughly the same time each day.

> The team will also check in with you twice, to ensure all is well with the medication


Study visit

> You will be asked to come back to the Warneford Hospital after taking the study medication. During this visit you be asked to complete further questionnaires and computer tasks.

What is the benefit for me?

Welchen Nutzen habe ich davon?

You will receive £125 in total for completing the study. We will also reimburse any travel expenses

You may enjoy being part of a research study, and you will be contributing to scientific knowledge and helping our long-term goal of improving treatment for psychiatric disorders.

Who is the study for? 

Für wen ist die Studie geeignet?

●       You have recovered from depression

●       You have previously had two or more episodes of depression. This can be self-diagnosed

●       Aged 18-55 years.

●       You are not pregnant, trying to get pregnant, or currently breastfeeding

●       You are not a heavy smoker, drinker or drug user

Complete this questionnaire to take part.

Fülle diesen Fragebogen aus, um herauszufinden, ob Du berechtigt bist